Syncephalastrum is a very rare causative agent of human zygomycosis. Syncephalastrum is a heterothallic filamentous fungus of the family zygomycete that is found in soil and animal feces primarily in tropical and subtropical areas. Syncephalastrum racemosum cohn colony characteristics. The term mucormycosis describes a group of diseases caused by fungi that belong to the order mucorales. A very rapidlygrowing fungus that produces a light to dark gray colony within three days, when incubated at 25oc 77of. Sinoorbital infection by syncephalastrum racemosum in chronic hepatorenal disease. Pdf intraabdominal zygomycosis caused by syncephalastrum. Molecular characterization and in vitro antifungal. We describe the first recorded case of invasive rhinoorbital infection with the zygomycete syncephalastrum racemosum in a 45yearold male patient with chronic hepatitis b infection, along with cirrhosis of liver. The efficacy of nematicidal strain syncephalastrum racemosum article in annals of microbiology 583. Germination of syncephalastrum racemosum sporangiospores was studied in shake flask and batch fermenter cultures. Syncephalastrum racemosum is the type species of the genus and a potential human pathogen. Syncephalastrum is the only genus in the syncephalastraceae family in the order mucorales.
Syncephalastrum wikispecies wikispecies, free species. Rhinoorbitalcerebral infection by syncephalastrum racemosusm alice j mathuram, promila mohanraj, mary s mathews abstract invasive rhinosinusitis infection has been known to be caused by zygomycetes commonly belonging to the genera rhizopus, mucor and rhizomucor. Syncephalastrum has also been isolated from normal finger and toenail clippings from several egyptian students who had no clinical disease. See the summary of synonyms and obselete names for the syncephalastrum spp. Structure and biochemistry of the spore surface of. These laboratories are expected to identify fungal pathogens to the genus and species level for detail.
Freezefracture studies have revealed a surface layer of rodlets on spores ofsyncephalastrum racemosum. Great toenail onychomycosis caused by syncephalastrum. Cytotoxic lasiodiplodin derivatives from the fungus. Subcultures of syncephalastrum racemosum wfccucp0148, grown on potato dextrose agar pda, oxoid, kansas city, usa at 28 c for 120 h were stored and used to make the spore solutions. Dear editor, apropos, an informative report a rare case of subcutaneous mucormycosis due to syncephalastrum racemosum. Total dystrophic onychomycosis caused by syncephalastrum recemosum.
Emulsification and hydrolysis of oil by syncephalastrum racemosum. Pavlovic md, phd 1, nina bulajic md, phd 2 dermatology online journal 12 1. Ecofriendly chitosan production by syncephalastrum racemosum and application to the removal of acid orange 7. During october 2010 to 2011, the nematicidal effects of the syncephalastrum racemosum fungus and the nematicide, avermectin, alone or combined were tested against the rkn meloidogyne. Due to the existence of new methodologies that have reduced the production costs of microbiological chitosan, this paper puts forward the use of agroindustrial residues in. Evaluation of mandibular symmetry and morphology in adult patients with unilateral posterior crossbite. Effective biological control is need for controlling this destructive pathogen in organic farming system. Dec 22, 2015 read syncephalastrum racemosum amine oxidase with high catalytic efficiency toward ethanolamine and its application in ethanolamine determination, applied microbiology and biotechnology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Sinoorbital infection by syncephalastrum racemosum in chronic hepatorenal disease vp baradkar, meenakshi mathur, monalisa panda, simit kumar department of microbiology, lokmanya tilak municipal medical college and general hospital, sion, mumbai 400 022, india. Total dystrophic onychomycosis caused by syncephalastrum. Lipolytic activity of syncephalastrum racemosum sciencedirect. A rare case of subcutaneous mucormycosis due to syncephalastrum. Francois lette, zelalem temesgen, in neurology and clinical neuroscience, 2007. Syncephalastrum racemosum is a filamentous fungus clinical significance.
Syncephalastrum monosporum has three varieties zheng. The rootknot nematode rkn is one of the most damaging agricultural pests. Koirala institute of health sciences, dharan, nepal 2 department of dermatology, b. A rare case of subcutaneous mucormycosis due to syncephalastrum racemosum. Microbial transformation of laxogenin yielded thirteen previously undescribed metabolites. Text is available under the creative commons attributionsharealike license. The patient was successfully treated with topical nystatin. Syncephalastrum racemosum mainly catalyzes hydroxylation on b, c or d rings s. Purification and characterization of a thermostabilecellulose free xylanase from syncephalastrum racemosum. Thirteen previously undescribed metabolites were obtained and their structures were elucidated by spectroscopic analysis. Sinoorbital infection by syncephalastrum racemosum in chronic. Until now it has been debated whether this fungus can actually cause disease in humans.
The genus syncephalastrum is characterised by the formation of cylindrical merosporangia on a terminal swelling of the sporangiophore. We report a middle aged diabetic gentleman who had invasive rhinoorbital. Onychomycosis of toenails caused by syncephalastrum. Syncephalastrum are primarily present in tropical or subtropical regions, where they are saprobes commonly isolated from animal dung and soil. Syncephalastrum racemosum syncephalastrum species trichoderma species. Rhinoorbitalcerebral infection by syncephalastrum racemosusm. Identification of a fungal protein of syncephalastrum. Our screening study yielded a copper amine oxidase sraox from syncephalastrum racemosum, which showed much higher affinity and catalytic efficiency toward ethanolamine ea than any other amine oxidase aox. Molecular characterization and in vitro antifungal susceptibility of 80 clinical isolates of mucormycetes. Syncephalastrum racemosum has been found widely in the environment. Very few cases of human disease caused by this particular fungus have been documented. Syncephalastrum racemosum has been used to produce an aspartic proteinase syncephapepsin with properties comparable to commericially available products ho et al. Analysis of the extracts indicated the presence of a glycoprotein with a molecular weight of approximately 12,000.
This organism is widely regarded as being nonpathogenic to humans, with only a single case of a cutaneous infection reported 1980. Syncephalastrum racemosum is a fungus belonging to zygomycetes. Efficacy evaluation of fungus syncephalastrum racemosum and. Colonies mea expanding, with abundant aerial mycelium, greyish. Great toenail onychomycosis caused by syncephalastrum racemosum. Syncephalastrum racemosumt applied and environmental asm. Pdf a rare case of subcutaneous mucormycosis due to. Browsing zygomycota by subject syncephalastrum racemosum. We report a rare case of onychomycosis caused by syncephalastrum racemosum in a 50yearold diabetic patient. Ecofriendly chitosan production by syncephalastrum racemosum. Sir, syncephalastrum species is a fungus belonging to the class zygomycetes and order mucorale.
This category is for the laboratories that examine specimens for the pathogenic molds and yeasts encountered in a clinical microbiology laboratory. Bensch westerdijk fungal biodiversity institute, uppsalalaan 8, utrecht, the netherlands botanische staatssammlung munchen, menzinger stra. During october 2010 to 2011, the nematicidal effects of the syncephalastrum racemosum fungus and the nematicide, avermectin, alone or combined were tested against the rkn meloidogyne incognita on cucumber under. It has worldwide distribution and is mainly found in dung and soil in tropical and subtropical regions. Lipolytic activity of syncephalastrum racemosum journal of dairy. The patients nail was surgically excised and thorough debridement was done. On abdominal examination, there was no guarding, rigidity, free fluid.
Sinoorbital infection by syncephalastrum racemosum in. Mycology proficiency testing program ptp category description. Microbial transformation of laxogenin by the fungus. Syncephalastrum species producing mycetomalike lesions. Ecofriendly chitosan production by syncephalastrum racemosum and application to the removal of acid orange 7 ao7 from wastewaters.
A sporangium can be globose to obovoid or flask or dumbbellshaped to somewhat cylindrical in a few taxa. Chopra, harish chander, and jasjit singh division of dairy bacteriology national dairy research institute, karnal haryana 2 001, india abstract lipase from syncephalastrum race mosum was recovered by ammonium sulphate precipitation and gel filtration on sephadex g75. The efficacy of nematicidal strain syncephalastrum racemosum. Contents of the allergy mixtures food mix and submixtures food mix contains all of the following submixtures, with all foods at roughly the same dilution relative to one another. Syncephalastrum species producing mycetomalike lesions ritu amatya 1, basudha khanal 1, arpana rijal 2 1 department of microbiology, b. Biotransformation of laxogenin lg, 1 was performed by the fungus syncephalastrum racemosum as 3. Mycology proficiency testing program wadsworth center. Chemical investigation of fungal biomass of the fungus syncephalastrum racemosum led to the isolation of new natural products 3r,5s5hydroxydeomethyllasiodiplodin 1, 6oxodeomethyllasiodiplodin 2, in addition to five known compounds, deomethyllasiodiplodin 3, lasiodiplodin 4, 3r,5r5hydroxydeomethyllasiodiplodin 5.
Following purification of the enzyme to electrophoretic homogeneity from a cell free extract, the maximum activity toward ea was. It can cause nail disease, especially in damaged nails. The fungus syncephalastrum racemosum cohn schroeter was found to transform the fungicide metalaxyl. Intraabdominal zygomycosis caused by syncephalastrum racemosum infection successfully treated with partial surgical debridement and highdose amphotericin b. Molecular characterization and in vitro antifungal susceptibility of 80 clinical isolates of mucormycetes in delhi, india. Sporangiospores are arranged in a single row within the merosporangia. Efficacy evaluation of fungus syncephalastrum racemosum. The influence of glucose availability on events during.
Unlike the pulmonary and central nervous system infections associated with other zygomycetes, syncephalastrum species is more likely to cause dermatomycoses and onychomycosis. Glucose was essential for initiation of these events. Intraabdominal zygomycosis caused by syncephalastrum racemosum infection successfully treated with partial surgical debridement and highdose amphotericin b lipid complex. Intraabdominal zygomycosis caused by syncephalastrum racemosum infection successfully treated with partial surgical debridement and highdose. Read identification of a fungal protein of syncephalastrum racemosum as aspartic proteinase, archives of biochemistry and biophysics on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. It has been isolated from air, soil rich in organic matter, caves, salt marshes. Jan 02, 2015 total dystrophic onychomycosis caused by syncephalastrum recemosum.
These flowers are just past their prime on 15 may 2015. Onychomycosis of toenails caused by syncephalastrum racemosum. References this zygomycotarelated article is a stub. Mar 16, 2015 we report a rare case of onychomycosis caused by syncephalastrum racemosum in a 50yearold diabetic patient. This article is or was the subject of a wiki education foundationsupported course assignment. Apropos, an informative report a rare case of subcutaneous mucormycosis due to syncephalastrum racemosum. An experimental study in a rat epigastric free flap model. Dec 31, 2011 instant access to the full article pdf. Syncephalastrum racemosum n 11, apophysomyces elegans n 2, a. It has been isolated from air, soil rich in organic matter, caves, salt marshes, salt water, mangrove swamps, polluted and stagnant fresh water, continue reading. Despite their common occurrences in tropical soil, they rarely cause diseases.
Pdf zygomycosis represent a group of uncommon but potentially fatal fungal infections. Continuing the research on chitosan extracted from strains of the mucorales order, amorim et al. Sporangiophores arising from rhizoids, irregularly branched, 1025. It has so far been isolated in cases of cutaneous infection and otomycosis.
In vitro antidiabetic activity of ethanolic and acetone extracts of endophytic fungi syncephalastrum racemosum isolated from the seaweed gracilaria corticata by alphaamylase inhibition assay method r. Syncephalastrum fungal genus microbiology dictionary. Intraabdominal zygomycosis caused by syncephalastrum. The genus syncephalastrum contains a single species. Syncephalastrum racemosum monotypic is common but comprises a small proportion of the fungal biota. Syncephalastrum racemosum edlab a very rapidlygrowing fungus that produces a light to dark gray colony within three days, when incubated at 25oc 77of. Analysis of the extracts indicated the presence of a glycoprotein with. Great toenail onychomycosis caused by syncephalastrum racemosum milos d. Syncephalastrum racemosum has some biotechnology applications as it been used to produce an aspartic proteinase syncephapepsin and both thermostable endoglucanase and cellulose free xylanase enzymes sapre et al. A case report ramya kumaran1, kg rudramurthy2 1tutor, department of microbiology, karuna medical college, palakkad, kerala, india, 2assistant professor, department of microbiology, karuna medical college, palakkad, kerala, india. Koirala institute of health sciences, dharan, nepal.
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